Book Summaries

Chapter 13: Pre-History (Genome)

•The surprising similarity of embryological genes in worms, flies, chicks and people sings an eloquent song of common descent. • D N A is a code written in a simple alphabet — a language. We compare the vocabulary of developmental genes and find the same words.

May 9, 2022Book Summaries

•The surprising similarity of embryological genes in worms, flies, chicks and people sings an eloquent song of common descent.

• D N A is a code written in a simple alphabet — a language. We compare the vocabulary of developmental genes and find the same words.

• On a completely different scale, but with direct analogy, the same is true of human language: by comparing the vocabularies of human languages, we can deduce their common ancestry.

• Historians may lament the lack of written records to document the distant, prehistoric past, but there is a written record, in the genes of living organisms.

•Basque, Navajo, and some Chinese tongues share an affinity not belonging to the Nostratic super-family of languages.

• It is speculated that Basque was once spoken in a larger area than currently, as shown by place names and Cro-Magnon cave paintings.

• There is a possibility that speakers of these tongues are actually descended from mesolithic people.

• Luigi Luca Cavalli-Sforza gathered data on common variations in simple genes to try and uncover any patterns.

• Five different contour maps of gene frequencies were uncovered within Europe – one gradient from south-east to north-west, one steep hill to the north=east, etc..

The most intriguing map was a steep little peak coinciding almost exactly with the greater (original) Basque country in northern Spain and southern France.

•There is a gene on chromosome 13 called BRCA2 that has been linked to breast cancer.

• This gene was first discovered by studying Icelandic families with a high incidence of breast cancer.

• Jewish people have a higher incidence of developing breast cancer due to a mutation in the BRCA2 gene.

• The ability to digest alcohol and milk are determined by genes on chromosomes 4 and 1 respectively.

•By looking at sixty-two separate cultures, two biologists were able to decide between these theories.

• They found no good correlation between the ability to drink milk and high latitudes, and no good correlation with arid landscapes.

• But they did find evidence that the people with the highest frequency of milk-digestion ability were ones with a history of pastoralism.

• The evidence suggests that such people took up a pastoral way of life first, and developed milk-digesting ability later in response to it.

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